Coexistence of lichen planus follicularis tumidus and Hashimoto's thyroiditis*
نویسندگان
چکیده
©2017 by Anais Brasileiros de Dermatologia Dear editor, As mentioned in the article in question, the selected control group had 21 volunteers without skin diseases and without gastrointestinal symptoms.1 This group was composed of people with similar socioeconomic status as the patients and who were accompanying those patients during the visits or who had been attended at a neighboring outpatient clinic. We agree that our control group had a small number of participants because of the difficulty in getting healthy people willing to undergo blood collection without any material gain in return. The methods for the diagnosis of Helicobacter pylori are divided into invasive and non-invasive. In our study, we used the Elisa serological test, a noninvasive method ideal for epidemiological studies, based on the identification of H. pylori-specific IgG antibodies in the patient’s serum. However, the has some restrictions. It only detects host exposure to the bacterium, without diagnosing active infection (true infection) (Krogfelt et al., 2005).2 We chose this method due to its reduced cost and the low complexity of accomplishment in relation to other diagnostic methods. We believe that the patient’s contact with H. pylori alone is sufficient to trigger the immunological cascade implicated in the pathogenesis of psoriasis. As in our study, Qayoom and Ahmad detected H. pylori antibodies in 40% of psoriasis patients and 10% of control subjects (healthy subjects without gastrointestinal complaints) and concluded that H. pylori plays a causal role in the pathogenesis of psoriasis.3 Similarly, Fathy et al. compared 20 plaque psoriasis patients with 20 healthy volunteers, matched for age and gender, and tested them for H. pilory antibodies using the Elisa test. The mean prevalence of seropositivity in psoriatic patients was significantly higher when compared to controls. Also, the high values correlated with the severity of the disease. They concluded that there is a link between H. pylori and psoriasis and that the bacterium may also influence the pathogenesis of the disease.4 q
منابع مشابه
Symmetrical drug-related intertriginous and flexural exanthema induced by clarithromycin*
of lichen planus follicularis tumidus and Hashimoto’s thyroiditis. An Bras Dermatol. 2017;92(4):585-7. Mailing address: Hatice Kaya Ozden Kocaeli Derince Training and Research Hospital Dermatology Department 41900 Kocaeli / Turkey E-mail: [email protected] We observed a slightly itchy, tumid, violaceous plaque in our patient only in the left retroauricular region and classic lichen planus lesion...
متن کاملFrontal Fibrosing Alopecia Coexisting with Lupus Erythematosus: Poor Response to Hydroxychloroquine
Lupus erythematosus, especially the discoid form, and lichen planopilaris may be associated and can occur in different topographies (coexistence) or in the same lesion (lupus eythematosus/lichen planus overlap syndrome). Frontal fibrosing alopecia is considered a variant form of lichen Received: October 24, 2016 Accepted: October 27, 2016 Published online: November 12, 2016 Leandro Noriega Derm...
متن کاملFrontal Fibrosing Alopecia Coexisting with Lupus Erythematosus: Poor Response to Hydroxychloroquine
Lupus erythematosus, especially the discoid form, and lichen planopilaris may be associated and can occur in different topographies (coexistence) or in the same lesion (lupus eythematosus/lichen planus overlap syndrome). Frontal fibrosing alopecia is considered a variant form of lichen Received: October 24, 2016 Accepted: October 27, 2016 Published online: November 12, 2016 Leandro Noriega Derm...
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عنوان ژورنال:
دوره 92 شماره
صفحات -
تاریخ انتشار 2017